Novel MAGicBead™ Technology

MAGicBead™ cfDNA Isolation Kit

Move away from traditional silica-based DNA binding chemistry with the MAGicBead™ cfDNA Isolation Kit. Eliminate alcohol-based washing and drying steps with an innovative DNA binding/release mechanism that is quick and efficient. Eluted cfDNA is free of enzymatic inhibitors that can interfere with PCR or other sensitive downstream applications, including Next-Gen Sequencing.

  • Highest Yield: Robust cfDNA isolation from up to 10 mL plasma w/ unique MAGicBead™ technology
  • Compatible: Any open automation platforms and a variety of biofluids, including plasma
  • NGS-Ready: High-quality cfDNA ideal for Next-Gen Sequencing and other applications

Streamlined Workflow with Superior Yields

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High cfDNA yields, minimize sample (target) drop-outs

Plasma cfDNA was extracted using three different magbead-based kits. Total yield was determined using the Qubit™ 1x dsDNA HS Assay Kit (Thermo Scientific)

Streamlining cfDNA workflows

Workflow

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Simple, scalable, and quick protocol that is easy to adopt on any automation platform or on lab bench.

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Efficiently scale your sample from 0.2 to 10mL

Ease of Use Facilitates Broad Compatibility

Sample Types Blood Tube Types (Plasma) Automation Platforms
  • Plasma
  • K2EDTA
  • KingFisher Flex/Apex (Thermo-Fisher)
  • Serum
  • Streck-DNA
  • Fluent® X (Tecan)
  • Saliva
  • K3EDTA
  • Microlab® STAR (Hamilton)
  • Urine
  • Na2EDTA
  • OT-2 (Opentrons)
  • Cerebrospinal fluid
  • Na-Citrate
  • Amniotic fluid
  • Na-F / K-Oxalate
  • Spent cell culture media
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    Compatible with wide variety of sample types

    500 μL of cerebrospinal fluid, amniotic fluid, spun-down saliva (12,000 x g for 5 min at RT) or 3 mL of urine

    Visualized using Cell-free DNA ScreenTape Analysis (Agilent Technologies)

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