DNA Clean-up and Concentration
Zymo Research's DNA clean-up and concentration technologies assure the purification of high-quality DNA with the complete removal of enzymatic inhibitors.
Go to Product Comparison Table
Product Comparison Table
| DNA Clean & Concentrator (DCC) | Genomic DNA Clean & Concentrator (gDCC) | Oligo Clean & Concentrator (OCC) | OneStep PCR Inhibitor Removal Kits | Zymoclean Gel DNA Recovery Kits | Zymoclean Large Fragment DNA Recovery Kit | Select-a-size DNA Clean & Concentrator Kits | |
|---|---|---|---|---|---|---|---|
| Nucleic Acid |
dsDNA |
dsDNA |
dsDNA dsRNA  ssRNA cDNA |
dsDNA dsRNA ssRNA cDNA |
dsDNA |
dsDNA |
dsDNA |
| Fragment Size | 50 bp — 10 kb | 10 kb — 200 kb | 16 — 200 nt | Only binds inhibitors | 50 bp — 10 kb | 10 kb — 200 kb | ≥ 50 bp |
| Format |
 Column 96-well Magnetic Bead |
Column96-well |
Column96-well |
Column96-well |
Column96-well |
Column |
ColumnMagnetic Bead |
| Common Applications | PCR
clean-up |
Extracted gDNA clean-up | Small oligo clean-up | Environmental inhibitor removal | DNA size selection from agarose gels | gDNA size selection from agarose gels | DNA & NGS library size selection |
| Removes | Salts, protein, unincorporated dyes/fluorescence and nucleotides, and phenol | Humic acids, tannins, polyphenolics, melanin | Salts, proteins, and unwanted fragments based on size | ||||
DNA Clean-up and Concentration Overview
High-quality, inhibitor-free DNA is a prerequisite for successful PCR, DNA ligation/cloning, sequencing, arrays, etc. The scientists at Zymo Research have developed the most comprehensive technologies for DNA clean-up and concentration from any preparation. Central to these products is the total removal of salts and alcohol from samples through the use of uniquely designed spin columns and plates that ensure complete elution of DNA without binding/wash buffer carryover. Coupled with uniquely formulated buffers, these DNA clean-up technologies assure the purification of high-quality DNA with the complete removal of enzymatic inhibitors.